Our common-sense responsibility concepts, it has been argued, prevent us from generating effective solutions to the climate change challenge. In response to this problem, I propose a new principle, namely individual-systemic responsibility, designed to overcome issues of harm recipient identifiability, cause-harm relation, ‘just’ attribution and distribution of responsibility, and blameworthiness. Individual-systemic responsibility is applicable to all social agents, from individual consumers and citizens to global corporations, under a general norm of equality in care and participative justice. This principle can be used to identify leverage points in steering social interdependencies from climate-harmful to climate-benign practices; to generate an order of (dis)engagement, when combined with considerations of opportunity and means; and to provide a normative basis for identifying, combating and preventing the moral fractures that lead global corporations to engage in systemically irresponsible behaviours and practices.